CD Markers
CD11

Author: Nat Pernick, M.D. (see Authors page)

Revised: 21 December 2015, last major update September 2013

Copyright: (c) 2003-2015, PathologyOutlines.com, Inc.

PubMed Search: CD11

Related topics: CD11a, CD11b, CD11c, CD11d

Definition / General
  • Alpha component of various integrins (CD11a, CD11b, CD11c, CD11d)
  • Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain
  • Adhesion molecules of the beta2 integrin family (CD11 / CD18) plays an essential role in neutrophil recruitment and activation during inflammation
Clinical Features