CD Markers
CD114



Topic Completed: 01 August 2013

Revised: 14 December 2018, last major update August 2013

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PubMed Search: CD114[title]
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Cite this page: Pernick N. CD114. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cdmarkerscd114.html. Accessed January 22nd, 2019.
Definition / general
  • Aka granulocyte colony-stimulating factor receptor, G-CSFR
  • Specific regulator of myeloid proliferation and differentiation
  • Mutations present in some patients with severe congenital neutropenia
Positive staining - normal
  • Granulocytes (all), monocytes, platelets, endothelium, placenta, trophoblastic cells
Positive staining - malignant
  • Cultured tumor cells
Negative staining
  • Eosinophils, lymphocytes, erythrocytes