Cite this page: Pernick N. CD130. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cdmarkerscd130.html. Accessed June 25th, 2019.
Definition / general
- Aka gp 130
- Required for transducing biological activities of IL6, IL11, leukemia inhibitory factor, ciliary neurotrophic factor, oncostatin M, and cardiotrophin-1
- IL6 and oncostatin M dependent activation of gp130 are involved in multiple myeloma
Positive staining - normal
- Almost all cell types (low levels)