CD Markers
CD130

Reviewer: Nat Pernick, M.D. (see Authors page)

Revised: 31 December 2015, last major update February 2002

Copyright: (c) 2002-2015, PathologyOutlines.com, Inc.

PubMed Search: CD130[title]
Cite this page: CD130. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cdmarkerscd130.html. Accessed December 2nd, 2016.
Definition / General
  • Aka gp 130
  • Required for transducing biological activities of IL6, IL11, leukemia inhibitory factor, ciliary neurotrophic factor, oncostatin M, and cardiotrophin-1
  • IL6 and oncostatin M dependent activation of gp130 are involved in multiple myeloma
Positive Staining - Normal
  • Almost all cell types (low levels)