CD Markers

Topic Completed: 1 February 2002

Minor changes: 9 November 2019

Copyright: (c) 2002-2019,, Inc.

PubMed Search: CD130[title]

Nat Pernick, M.D.
Page views in 2019: 42
Page views in 2020 to date: 32
Cite this page: Pernick N. CD130. website. Accessed August 13th, 2020.
Definition / general
  • Aka gp 130
  • Required for transducing biological activities of IL6, IL11, leukemia inhibitory factor, ciliary neurotrophic factor, oncostatin M, and cardiotrophin-1
  • IL6 and oncostatin M dependent activation of gp130 are involved in multiple myeloma
Positive staining - normal
  • Almost all cell types (low levels)
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