CD Markers
CD132

Reviewer: Nat Pernick, M.D. (see Authors page)

Revised: 31 December 2015, last major update February 2002

Copyright: (c) 2002-2015, PathologyOutlines.com, Inc.

PubMed Search: CD132[title]
Definition / General
  • Aka common cytokine receptor gamma chain - receptor for IL-2, IL-4, IL-7, IL-9 and IL-15
  • Mutation in humans causes X-linked severe combined immunodeficiency (no T cells, no NK cells)
  • CD132 is a target molecule for gene therapy for X-SCID
Positive Staining - Normal
  • T cells, B cells, NK cells, monocytes/macrophages, neutrophils