CD Markers

Reviewer: Nat Pernick, M.D. (see Authors page)

Revised: 4 January 2016, last major update February 2002

Copyright: (c) 2002-2016,, Inc.

PubMed Search: CD152[title]
Cite this page: CD152. website. Accessed October 19th, 2018.
Definition / general
  • Aka cytotoxic T lymphocyte-associated protein-4, CTLA4
  • Negative regulator of T cell activation
  • CTLA4 restriction fragment length polymorphisms are linked to various autoimmune disorders
  • Shares sequence homology with CD28; also shares ligands CD80 and CD86 with CD28
Positive staining - normal
  • Activated but not resting T cells, activated B cells
Additional references