CD Markers

Topic Completed: 1 February 2002

Revised:17 December 2018, last major update February 2002

Copyright: (c) 2002-2016,, Inc.

PubMed Search: CD152[title]

Nat Pernick, M.D.
Page views in 2019: 95
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Cite this page: Pernick N. CD152. website. Accessed August 13th, 2020.
Definition / general
  • Aka cytotoxic T lymphocyte-associated protein-4, CTLA4
  • Negative regulator of T cell activation
  • CTLA4 restriction fragment length polymorphisms are linked to various autoimmune disorders
  • Shares sequence homology with CD28; also shares ligands CD80 and CD86 with CD28
Positive staining - normal
  • Activated but not resting T cells, activated B cells
Additional references
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