CD Markers
CD158




Topic Completed: 1 February 2002

Revised: 17 December 2018, last major update February 2002

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: CD158

Related topics: CD158a, CD158b, Other CD158
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Cite this page: Pernick N. CD158. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cdmarkerscd158.html. Accessed May 23rd, 2019.
Definition / general
  • Member of KIR (killer cell immunoglobulin like receptor) family, also called killer cell inhibitory receptors
  • Binding by HLA class I molecules causes inhibition of NK or T cell cytotoxic activity
  • Melanoma specific cytotoxic T lymphocytes may express KIR and regulate their ability to kill these tumors
Positive staining - normal
  • Natural killer cells (NK cells), some T cells
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