CD Markers

Reviewer: Nat Pernick, M.D. (see Authors page)

Revised: 4 January 2016, last major update February 2002

Copyright: (c) 2002-2016,, Inc.

PubMed Search: CD158

Related topics: CD158a, CD158b, Other CD158
Cite this page: CD158. website. Accessed July 21st, 2018.
Definition / general
  • Member of KIR (killer cell immunoglobulin like receptor) family, also called killer cell inhibitory receptors
  • Binding by HLA class I molecules causes inhibition of NK or T cell cytotoxic activity
  • Melanoma specific cytotoxic T lymphocytes may express KIR and regulate their ability to kill these tumors
Positive staining - normal
  • Natural killer cells (NK cells), some T cells