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CD Markers

CD15u


Reviewers: Nat Pernick, M.D., (see Reviewers page)
Revised: 10 December 2010, last major update November 2010
Copyright: (c) 2002-2010, PathologyOutlines.com, Inc.

General
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● Adhesion protein representing the sulfated form of CD15

Terminology
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● Also called sialyl 6-sulfo Lewis X

Physiology
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● Major L-selectin ligand on high endothelial venules of human peripheral lymph nodes

Diagrams
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Uses by pathologists
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● No significant clinical use by pathologists

Positive staining (normal)
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● Neutrophils, basophils, mature granulocytes, monocytes, NK cells and T lymphocytes
● Also immature bone marrow cells, endothelial cells of high endothelium (HEV) of peripheral lymph nodes
● Expression on lymphocytes is variable depending on the antibodies used for detection

Positive staining (disease)
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● Myelomonocytic leukemia cells, adenocarcinoma

End of CD Markers > CD15u


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