CD Markers
CD17 / CDw17

Author: Nat Pernick, M.D. (see Authors page)

Revised: 22 December 2015, last major update December 2013

Copyright: (c) 2003-2015,, Inc.

PubMed Search: CD17, CDw17, Lactosylceramide[title]
Cite this page: CD17 / CDw17. website. Accessed October 25th, 2016.
Definition / General
  • Most abundant glycosphingolipid in neutrophils; NOT a protein
  • Also known as lactosylceramide
  • "CD17" is also a type of mutation in beta-thalassemia, unrelated to CD markers (Fetal Diagn Ther 2010;27:25)
Clinical Features
  • Elevated levels are present in plasma of patients with familial hypercholesterolemia, and in plaque intima of aorta in patients who died of cardiovascular disease (Proc Natl Acad Sci U S A 2004;101:6490)
Uses by Pathologists
  • No significant clinical use by pathologists
Positive Staining - Normal
  • Granulocytes, macrophages / monocytes, platelets, basophils, CD19+ B cells and tonsillar dendritic cells