CD Markers
CD171


Topic Completed: 1 February 2002

Revised: 18 December 2018, last major update February 2002

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: CD171 or L1

Nat Pernick, M.D.
Page views in 2018: 39
Page views in 2019 to date: 89
Cite this page: Pernick N. CD171. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cdmarkerscd171.html. Accessed December 5th, 2019.
Definition / general
  • Aka L1
  • Adhesion molecule required for normal neurohistogenesis
  • Mutations cause CRASH (Corpus callosum hypoplasia/agenesis, Retardation, Aphasia, Spastic paraplegia/shuffling gait and Hydrocephalus due to stenosis of aqueduct of Sylvius), an X linked neurologic disorder
  • May mediate kidney branching morphogenesis, maintenance of lymph node architecture during immune response, co-stimulation of T-cell activation in vitro
Positive staining - normal
  • Post-mitotic neurons, glia, epithelial cells (some), lymphoid cells (some), myeloid (some), monocytes
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