General
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• Aka Tn
• Simple mucin-type carbohydrate antigen produced in the initial steps of mucin biosynthetic pathway, due to aberrant or incomplete glycosylation of mucins

General
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• Aka Sialyl Tn (STN)
• Carbohydrate associated with apomucins MUC1, MUC2; produced in the initial steps of mucin biosynthetic pathway
• Presence associated with aggressive tumors
• High pre-operative serum levels predict liver metastasis and poor prognosis after resection for gastric cancer
• Definitive Phase III trial of STN vaccine in metastatic breast cancer patients began 2001

Positive staining (tumors)
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• Carcinomas

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