CD Markers
CD179


Topic Completed: 1 February 2002

Revised: 14 December 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

Nat Pernick, M.D.
Page views in 2019: 54
Page views in 2020 to date: 13
Cite this page: Pernick N. CD179. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cdmarkerscd179.html. Accessed February 27th, 2020.
Definition / general
  • CD179a:
    • Aka VpreB1
    • Associates non-covalently with CD179b to form surrogate light chain as component of preB cell receptor, which plays a critical role in early B cell differentiation
  • CD179b:
    • Aka lambda-5
    • Associates non-covalently with CD179a to form surrogate light chain as component of preB cell receptor, which plays a critical role in early B cell differentiation
    • Mutations impair B cell development and cause agammaglobulinemia
Positive staining - normal
  • PreB cells
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