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General
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Physiology
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Diagrams
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CD20 expression during B cell development

Clinical features
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Uses by pathologists
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Case reports
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Micro images
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Various images



Non-neoplastic:

Bladder: follicular cystitis

Breast: lymphocytic mastitis (fig A)

Lymph node: angiomyomatous hamartoma

Lymph node: infarction

Skin: halo nevus



Diffuse large B cell lymphoma:

Bone

Breast (right)

Heart (fig 8, right atrium)

Mediastinum


Brain


Intravascular


Nasal cavity (fig 3A)

Ovary (fig 3)

Prostate

Skin (fig D)



Other leukemia / lymphoma:

Angioimmunoblastic
T cell lymphoma (fig d)

B-ALL (mature) of bone
marrow (fig 2: inset)

Bone marrow infiltration by
unspecified B cell lymphoma (fig C)


Follicular lymphoma

Neoplastic T cells (fig b)

Burkitt lymphoma of ileocecal valve
(contributed by Dr. Kaveh Naemi, California)


Hairy cell leukemia; right: variant type (fig D)

Hodgkin lymphoma: left-lymphocyte predominant cells are CD20+ (figs C&D); right-fig C


Hodgkin lymphoma, nodular lymphocyte predominant subtype: small lymphocytes and LP cells are CD20+, but classic RS cells are CD20-

Hodgkin lymphoma: Reed–Sternberg cells


Lymphoplasmacytic lymphoma / Waldenström macroglobulinemia (brain, fig D)


MALT lymphoma of liver (left), lung (middle), stomach (right)


Mantle cell lymphoma of prostate (fig 5)

Marginal zone lymphoma of prostate (fig 7)

Myeloid sarcoma of bone (negative)

NK/T cell lymphoma, nasal type (tumor cells are negative)


Left: SLL of breast; right: SLL of colon (fig C)

T cell lymphoma; right: fig A




Post-transplantation lymphoproliferative disorder:

Liver; right side fig 3 is CD20



Other neoplasms:

Immunoblastic myofibroblastic tumor (reactive B cells, fig 2d)


Thymomas, various


Thymoma, ectopic
hamartomatous (fig C)

Thymoma, lymphocyte
predominant (CD20-)


Virtual slides
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Diffuse large B cell lymphoma

Positive staining - normal
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Positive staining - disease
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Negative staining
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Flow cytometry description
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Flow cytometry images
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Hairy cell leukemia variant (fig A): CD20 (bright) and CD22+



End of CD Markers > CD20



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