CD Markers
CD201
Revised: 18 December 2018, last major update August 2013
Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.
PubMed Search: CD201
CD201
Author: Nat Pernick, M.D.
Topic Completed: 1 August 2013
Revised: 18 December 2018, last major update August 2013
Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.
PubMed Search: CD201
Cite this page: Pernick N. CD201. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cdmarkerscd201.html. Accessed August 13th, 2020.
Definition / general
- Binds protein C in a calcium-dependent manner
- Aka Endothelial Protein C Receptor (EPC R), protein C receptor
- Protein C is a vitamin K dependent enzyme with major role in coagulation of blood; activated when thrombin binds to thrombomodulin on endothelium.
- Mutations in CD201 and thrombomodulin associated with late fetal loss; similar mutation associated with venous thromboembolism and myocardial infarction
Positive staining - normal
- Endothelial cells (not in liver and kidney)
