CD Markers
CD201

Author: Nat Pernick, M.D. (see Authors page)

Revised: 6 January 2016, last major update August 2013

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PubMed Search: CD201
Definition / General
  • Binds protein C in a calcium-dependent manner
  • Aka Endothelial Protein C Receptor (EPC R), protein C receptor
  • Protein C is a vitamin K dependent enzyme with major role in coagulation of blood; activated when thrombin binds to thrombomodulin on endothelium.
  • Mutations in CD201 and thrombomodulin associated with late fetal loss; similar mutation associated with venous thromboembolism and myocardial infarction
Positive Staining - Normal
  • Endothelial cells (not in liver and kidney)