Pathology Outlines

CD Markers
CD201

Topic Completed: 1 August 2013

Revised: 18 December 2018, last major update August 2013

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed Search: CD201

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Table of Contents

Definition / general | Positive staining - normal

Cite this page: Pernick N. CD201. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cdmarkerscd201.html. Accessed December 12th, 2019.

Definition / general

Binds protein C in a calcium-dependent manner
Aka Endothelial Protein C Receptor (EPC R), protein C receptor
Protein C is a vitamin K dependent enzyme with major role in coagulation of blood; activated when thrombin binds to thrombomodulin on endothelium.
Mutations in CD201 and thrombomodulin associated with late fetal loss; similar mutation associated with venous thromboembolism and myocardial infarction

Positive staining - normal

Endothelial cells (not in liver and kidney)