CD Markers
CD201



Topic Completed: 1 August 2013

Revised: 18 December 2018, last major update August 2013

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PubMed Search: CD201
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Cite this page: Pernick N. CD201. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cdmarkerscd201.html. Accessed March 20th, 2019.
Definition / general
  • Binds protein C in a calcium-dependent manner
  • Aka Endothelial Protein C Receptor (EPC R), protein C receptor
  • Protein C is a vitamin K dependent enzyme with major role in coagulation of blood; activated when thrombin binds to thrombomodulin on endothelium.
  • Mutations in CD201 and thrombomodulin associated with late fetal loss; similar mutation associated with venous thromboembolism and myocardial infarction
Positive staining - normal
  • Endothelial cells (not in liver and kidney)
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