CD Markers
CD202b

Author: Nat Pernick, M.D. (see Authors page)

Revised: 6 January 2016, last major update August 2013

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed Search: CD202b
Definition / General
  • Aka Tie2 (Tyrosine kinase with Ig-like loops and Epidermal growth factor homology domains), aka Tek
  • Receptor tyrosine kinase at #9p21, binds to angiopoietin-1
  • May be earliest mammalian endothelial cell lineage marker
  • Involved in vein morphogenesis and communication between endothelial and smooth muscle cells for remodeling and repair of blood vessels
  • Defects associated with inherited venous malformations
Positive Staining - Normal
  • Endothelial cells, hematopoietic cells