CD Markers

Topic Completed: 1 August 2013

Revised: 18 December 2018, last major update August 2013

Copyright: (c) 2003-2016,, Inc.

PubMed Search: CD207

Nat Pernick, M.D.
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Cite this page: Pernick N. CD207. website. Accessed October 29th, 2020.
Definition / general
  • Aka langerin (Langerhans cell specific c-type lectin)
  • Functions as endocytic receptor
  • Localized to Birbeck granules
  • Mannose binding to this protein may cause antigen internalization into Birbeck granules and access to a nonclassical antigen-processing pathway
Positive staining - normal
  • Langerhans cells (immature dendritic cells of epidermis and mucosa)
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