CD Markers
CD207



Topic Completed: 1 August 2013

Revised: 18 December 2018, last major update August 2013

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PubMed Search: CD207
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Cite this page: Pernick N. CD207. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cdmarkerscd207.html. Accessed March 25th, 2019.
Definition / general
  • Aka langerin (Langerhans cell specific c-type lectin)
  • Functions as endocytic receptor
  • Localized to Birbeck granules
  • Mannose binding to this protein may cause antigen internalization into Birbeck granules and access to a nonclassical antigen-processing pathway
Positive staining - normal
  • Langerhans cells (immature dendritic cells of epidermis and mucosa)
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