CD Markers
CD207

Author: Nat Pernick, M.D. (see Authors page)

Revised: 6 January 2016, last major update August 2013

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PubMed Search: CD207
Definition / General
  • Aka langerin (Langerhans cell specific c-type lectin)
  • Functions as endocytic receptor
  • Localized to Birbeck granules
  • Mannose binding to this protein may cause antigen internalization into Birbeck granules and access to a nonclassical antigen-processing pathway
Positive Staining - Normal
  • Langerhans cells (immature dendritic cells of epidermis and mucosa)