CD Markers

Topic Completed: 1 February 2002

Revised: 18 December 2018, last major update February 2002

Copyright: (c) 2002-2016,, Inc.

PubMed Search: CD221 or insulin-like growth factor 1 receptor [title]

Nat Pernick, M.D.
Page views in 2019: 24
Page views in 2020 to date: 20
Table of Contents
Definition / general
Cite this page: Pernick N. CD221. website. Accessed August 13th, 2020.
Definition / general
  • Aka insulin-like growth factor 1 receptor
  • Mediates insulin stimulated DNA synthesis and IGF1 stimulated cell proliferation and differentiation
  • Often overexpressed in malignant tissue, where it functions as an anti-apoptotic agent by enhancing cell survival
Back to top