CD Markers
CD221

Author: Nat Pernick, M.D. (see Authors page)

Revised: 7 Janaury 2016, last major update February 2002

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: CD221 or insulin-like growth factor 1 receptor [title]
Table of Contents
Definition / General
Definition / General
  • Aka insulin-like growth factor 1 receptor
  • Mediates insulin stimulated DNA synthesis and IGF1 stimulated cell proliferation and differentiation
  • Often overexpressed in malignant tissue, where it functions as an anti-apoptotic agent by enhancing cell survival