Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 22 August 2013, last major update February 2002
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.
PubMed Search: CD221
- Aka insulin-like growth factor 1 receptor
- Mediates insulin stimulated DNA synthesis and IGF1 stimulated cell proliferation and differentiation
- Often overexpressed in malignant tissue, where it functions as an anti-apoptotic agent by enhancing cell survival
End of CD Markers > CD221
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