CD Markers
CD221


Topic Completed: 1 February 2002

Revised: 18 December 2018, last major update February 2002

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: CD221 or insulin-like growth factor 1 receptor [title]

Nat Pernick, M.D.
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Table of Contents
Definition / general
Cite this page: Pernick N. CD221. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cdmarkerscd221.html. Accessed November 20th, 2019.
Definition / general
  • Aka insulin-like growth factor 1 receptor
  • Mediates insulin stimulated DNA synthesis and IGF1 stimulated cell proliferation and differentiation
  • Often overexpressed in malignant tissue, where it functions as an anti-apoptotic agent by enhancing cell survival
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