Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 22 August 2013, last major update February 2002
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.
PubMed Search: CD223
- Aka Lymphocyte-Activation Gene 3 (LAG-3)
- Homologous to CD4
- Associates with MHC class II molecules on monocytes/dendritic cells, which are subsequently activated
- May help activated CD4+ and CD8+ T cells to fully activate monocytes and dendritic cells, leading to optimized MHC class I and class II T cell responses
Positive staining (normal)
- Activated T cells, activated NK cells
End of CD Markers > CD223
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.
All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com
with any questions (click here for other