CD Markers

Topic Completed: 1 August 2013

Revised: 19 December 2018, last major update August 2013

Copyright: (c) 2003-2016,, Inc.

PubMed Search: Fy glycoprotein

Nat Pernick, M.D.
Page views in 2019: 30
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Cite this page: Pernick N. CD234. website. Accessed August 13th, 2020.
Definition / general
  • Aka Duffy blood group antigen (Fy glycoprotein); erythrocyte chemokine receptor, Duffy Antigen Receptor for Chemokines (DARC)
  • RBC receptor for Plasmodium vivax, a malarial parasite
  • Negativity associated with sickle cell trait, due to common protection against malaria provided by both traits African-Americans often Duffy negative and resistant to P. vivax malaria
Positive staining - normal
  • Endothelial cells of postcapillary venules, Purkinje cells of cerebellum
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