Pathology Outlines

CD Markers
CD234

Author: Nat Pernick, M.D. (see Authors page)

Revised: 7 January 2016, last major update August 2013

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed Search: Fy glycoprotein

Table of Contents

Definition / general | Positive staining - normal

Cite this page: CD234. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cdmarkerscd234.html. Accessed April 25th, 2018.

Definition / general

Aka Duffy blood group antigen (Fy glycoprotein); erythrocyte chemokine receptor, Duffy Antigen Receptor for Chemokines (DARC)
RBC receptor for Plasmodium vivax, a malarial parasite
Negativity associated with sickle cell trait, due to common protection against malaria provided by both traits African-Americans often Duffy negative and resistant to P. vivax malaria

Positive staining - normal

Endothelial cells of post-capillary venules, Purkinje cells of cerebellum