CD Markers
CD234



Topic Completed: 1 August 2013

Revised: 19 December 2018, last major update August 2013

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PubMed Search: Fy glycoprotein
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Cite this page: Pernick N. CD234. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cdmarkerscd234.html. Accessed March 25th, 2019.
Definition / general
  • Aka Duffy blood group antigen (Fy glycoprotein); erythrocyte chemokine receptor, Duffy Antigen Receptor for Chemokines (DARC)
  • RBC receptor for Plasmodium vivax, a malarial parasite
  • Negativity associated with sickle cell trait, due to common protection against malaria provided by both traits African-Americans often Duffy negative and resistant to P. vivax malaria
Positive staining - normal
  • Endothelial cells of postcapillary venules, Purkinje cells of cerebellum
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