CD Markers
CD234

Author: Nat Pernick, M.D. (see Authors page)

Revised: 12 September 2018, last major update August 2013

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed Search: Fy glycoprotein
Cite this page: CD234. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cdmarkerscd234.html. Accessed October 19th, 2018.
Definition / general
  • Aka Duffy blood group antigen (Fy glycoprotein); erythrocyte chemokine receptor, Duffy Antigen Receptor for Chemokines (DARC)
  • RBC receptor for Plasmodium vivax, a malarial parasite
  • Negativity associated with sickle cell trait, due to common protection against malaria provided by both traits African-Americans often Duffy negative and resistant to P. vivax malaria
Positive staining - normal
  • Endothelial cells of postcapillary venules, Purkinje cells of cerebellum