CD Markers
CD245

Author: Nat Pernick, M.D. (see Authors page)

Revised: 21 June 2016, last major update February 2002

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: p220 or p240 [title]
Cite this page: CD245. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cdmarkerscd245.html. Accessed December 4th, 2016.
Definition / General
  • Also called p220/240
  • Very little information is available for CD245 directly; appears to be identical to NPAT (nuclear protein, ataxia-telangiectasia locus)
  • NPAT links S phase cyclin E/Cdk2 kinase activity to replication-dependent histone gene transcription (Biochemistry 2006;45:15915, Mol Cell Biol 2005;25:6140)
Uses by Pathologists
  • No significant clinical use by pathologists
Positive Staining - Normal