CD Markers - CD2R

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CD Markers

CD2R

Reviewers: Nat Pernick, M.D., (see Reviewers page)
Revised: 29 November 2010, last major update November 2010
Copyright: (c) 2002-2010, PathologyOutlines.com, Inc.

General
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● CD2 epitope present on activated T cells, unmasked by conformational change of CD2 glycoprotein during activation

Uses by pathologists
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● No significant clinical use by pathologists

Positive staining (normal)
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● Activated T cells

Positive staining (disease)
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● Blood and synovial fluid T cells in rheumatoid arthritis; peripheral blood T cells in juvenile rheumatoid arthritis, SLE, ankylosing spondylitis and Lyme disease (Scand J Immunol 1991;34:351)

Negative staining
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● Resting T cells

End of CD Markers > CD2R

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