CD Markers

Author: Nat Pernick, M.D. (see Authors page)

Revised: 30 December 2015, last major update January 2011

Copyright: (c) 2002-2015,, Inc.

PubMed Search: CD37 [title]
Cite this page: CD37. website. Accessed October 19th, 2018.
Definition / general
  • Member of tetraspanin family (members have 4 hydrophobic domains, others are CD9, CD53, CD63, CD81, CD82 and CD151)
  • Regulates T cell proliferation (J Immunol 2004;172:2953)
Clinical features
Uses by pathologists
  • No significant clinical use by pathologists
Positive staining - normal
  • B cells, T cells (low), neutrophils (low), monocytes (low), macrophages, dendritic cells
Positive staining - disease
Negative staining
  • NK cells, platelets, erythrocytes, plasma cells
  • Plasma cell neoplasms, preB-ALL (or low)
Additional references