Home   Chapter Home   Jobs   Conferences   Fellowships   Books



Advertisement

CD Markers
CD5

Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 25 August 2013, last major update August 2013
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.

General
=========================================================================

Physiology
=========================================================================

Clinical features
=========================================================================

Uses by pathologists
=========================================================================

Micro images
=========================================================================


Tumors / tissue typically CD5+

Breast CLL/SLL, by Dr. Julia Braza, Boston, MA (USA)

Eyelid: mantle cell lymphoma

Lymph node: mantle cell lymphoma (fig b)

Lymph node: SLL


Tonsil: normal

Thyroid: CASTLE tumor

Thymic carcinoma,
nonkeratinizing squamous cell subtype


Various images (quality control)



Tumors / tissue occasionally / rarely CD5+

Bone marrow:
lymphoplasmacytic lymphoma (fig A)

Breast: florid ductal epithelial hyperplasia and normal ducts with 4C7 antibody


Liver: diffuse
large B cell lymphoma (fig C)

Liver: MALT lymphoma is CD5-


Lymph node: diffuse
large B cell lymphoma

Lymph node: follicular lymphoma: typically CD5 stains only adjacent T cells (left); rarely tumor is CD5+ (right)


Marginal zone lymphomas are rarely CD5+

Conjunctiva (fig 2B)

Lung (fig A)

Spleen (fig B)

Positive staining - normal
=========================================================================

Positive staining - disease
=========================================================================

Negative staining
=========================================================================

End of CD Markers > CD5


This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).