CD Markers

Reviewer: Nat Pernick, M.D. (see Authors page)

Revised: 31 July 2018, last major update February 2002

Copyright: (c) 2002-2018,, Inc.

PubMed Search: CD58[title]
Cite this page: Pernick, N. CD58. website. Accessed September 25th, 2018.
Definition / general
Uses by pathologists
Microscopic (histologic) images

Images hosted on other servers:

Buccal mucosa:
stratified squamous
epithelium (LFA-3+)

Cardiac muscle:
intercalated discs
and capillary
endothelium (LFA-3+)

Cerebellum: cortical microglia (A, LFA-3+); liver: Kupffer cells (B, LFA-3+); skin: epidermal dendritic cell (C, LFA-3 +)

Kidney: proximal tubule (LFA-3+, p) and distal tubule (d) epithelial cells with central, spherical nuclei (LFA-3 negative)

Testis: cells close to seminiferous tubule boundary, reminiscent of Sertoli cells

Positive staining - normal
  • Leukocytes (but not mature B cells), pre B cells, erythrocytes, endothelial cells, epithelial cells, fibroblasts and cardiac muscle (J Clin Pathol 1990;43:893)
Positive staining - disease
Negative staining
  • Mature B cells