CD Markers

Topic Completed: 1 February 2002

Minor changes: 21 August 2019

Copyright: (c) 2002-2018,, Inc.

PubMed Search: CD58[title]

Nat Pernick, M.D.
Page views in 2019: 658
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Cite this page: Pernick N. CD58. website. Accessed August 13th, 2020.
Definition / general
Uses by pathologists
Microscopic (histologic) images

Images hosted on other servers:
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Buccal mucosa:
stratified squamous
epithelium (LFA-3+)

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Cardiac muscle:
intercalated discs
and capillary
endothelium (LFA-3+)

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Cerebellum: cortical microglia (A, LFA-3+); liver: Kupffer cells (B, LFA-3+); skin: epidermal dendritic cell (C, LFA-3 +)

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Kidney: proximal tubule (LFA-3+, p) and distal tubule (d) epithelial cells with central, spherical nuclei (LFA-3 negative)

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Testis: cells close to seminiferous tubule boundary, reminiscent of Sertoli cells

Positive staining - normal
  • Leukocytes (but not mature B cells), pre B cells, erythrocytes, endothelial cells, epithelial cells, fibroblasts and cardiac muscle (J Clin Pathol 1990;43:893)
Positive staining - disease
Negative staining
  • Mature B cells
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