CD Markers
CD66d

Author: Nat Pernick, M.D. (see Authors page)

Revised: 24 November 2015, last major update November 2014

Copyright: (c) 2003-2015, PathologyOutlines.com, Inc.

PubMed Search: CD66d

Related topics: General, CD66b, CD66c, CD66e / CEA, CD66f

Cite this page: CD66d. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cdmarkerscd66d.html. Accessed May 26th, 2018.
Definition / general
  • Also called CEACAM3, CGM1
  • Cell adhesion molecule capable of activating neutrophils
  • Has important role in control of pathogens by the innate (opsonin-independent) immune system (J Exp Med 2004;199:35)
  • Used by Neisseria. gonorrhoeae, Moraxella catarrhalis and Hemophilus influenzae to anchor themselves to and invade host cells
  • N. gonorrheae has an opacity-associated (Opa) protein that binds to CEACAM3 (J Biol Chem 2001;276:17413)
  • References: OMIM #609142
Uses by pathologists
  • No significant clinical use by pathologists
Positive staining - normal
  • Granulocytes