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CD Markers
CD68

Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 20 September 2013, last major update February 2002
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.
PubMed Search: CD68[title]

General
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Uses by pathologists
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Micro images
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Acute demyelinating disease (fig 9)

AML-M4 (fig 12)

AML-M5 (fig 5b)

Atypical epithelioid angiomyolipoma of kidney


Breast carcinoma: treatment effect (fig 3)

Cholesterol granuloma of temporal bone

Castlemanís disease

Chronic myelomonocytic leukemia with eosinophilia
(fig C)


Crohnís disease

Crystal storing histiocytosis within lymphoma (fig 9)

Endometrial nodular histiocytic hyperplasia
(fig 3)


Erdheim-Chester disease: #1-lung (fig 5); #2-liver (fig 5)

Follicular dendritic cell tumor (fig 13)

Gastrointestinal stromal tumor with osteoclast-like giant cells (fig b)


Gaucherís disease (presumptive) in spleen

Giant cell granuloma of temporal bone (fig C)

Granular cell tumor (fig 2B)

Histiocytic sarcoma (fig 5)


HIV associated encephalopathy

Inflammatory demyelinating pseudotumor (brain)

Juvenile xanthogranuloma: adult (fig 4)

Kikuchiís disease (fig 13)


Kikuchi-like lymphadenopathy #1 in lupus

Kupffer cells in alcoholic liver disease (fig 6)


Leiomyosarcoma with osteoclast-like giant cells (fig D)

Lymph node-tingible body macrophages

Multiple sclerosis


Myeloid sarcoma #1 (fig 1d); #2-spine; #3-uterus

Plexiform fibrohistiocytic tumor (fig 3)


Plasmacytoid monocyte tumor

Rosai-Dorfman disease (fig D)

Splenic hamartoma (figure 3B)

Thyroid gland giant cell granuloma
(fig C)


Viral myocarditis

Xanthogranulomatous pyelonephritis (fig 4)

  

Various images: quality control

Kupffer cells in normal liver

Kupffer cells in severe non-
alcoholic steatohepatitis (fig B)


Positive staining - normal
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Positive staining - tumors
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Negative staining
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End of CD Markers > CD68


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