CD Markers

Reviewer: Nat Pernick, M.D. (see Authors page)

Revised: 31 December 2015, last major update February 2002

Copyright: (c) 2002-2015,, Inc.

PubMed Search: CD85j

Related topics: CD85, CD85A, CD85B, CD85C, CD85D, CD85E, CD85F, CD85G, CD85H, CD85I, CD85K, CD85L, CD85M
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Cite this page: CD85J. website. Accessed September 23rd, 2019.
Definition / general
  • Also called CD85, LIR1, ILT2, MIR7, LILRB1
  • Transduces negative signals that prevent killing of MHC class I expressing cells
  • Binds classical (HLA-A and -B) and non-classical (HLA-G, -E and -F) MHC class I molecules
  • Upregulated by HLA-G in antigen-presenting cells, NK cells, and T cells (FASEB J 2005;19:662)
  • Receptor for CMV UL18 protein, which resembles MHC class I molecules (J Virol 2005;79:2251)
Uses by pathologists
  • No significant clinical use by pathologists
Positive staining - normal
  • B cells, monocytes, dendritic cells (low), T cells (some), NK cells (some)
Additional references
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