CD Markers

Reviewer: Nat Pernick, M.D. (see Authors page)

Revised: 31 December 2015, last major update February 2002

Copyright: (c) 2002-2015,, Inc.

PubMed Search: CD85k

Related topics: CD85, CD85A, CD85B, CD85C, CD85D, CD85E, CD85F, CD85G, CD85H, CD85I, CD85J, CD85L, CD85M
Page views in 2018: 9
Page views in 2019 to date: 11
Cite this page: CD85K. website. Accessed September 23rd, 2019.
Definition / general
  • Also called ILT3, LIR5, HM18, LILRB4
  • Upregulated by HLA-G in antigen-presenting cells, NK cells, and T cells (FASEB J 2005;19:662)
  • Receptor for class I MHC antigens
  • Recognizes broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles
  • Involved in downregulation of immune response and development of tolerance, including transplants (Int Immunol 2004;16:1055)
  • Aspirin use is associated with upregulation (Am J Transplant 2006;6:2046)
Uses by pathologists
  • No significant clinical use by pathologists
Positive staining - normal
Additional references
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