Cervix
Carcinoma
WHO classification of cervical tumors

Author: Ashwyna Sunassee, M.D. (see Authors page)

Revised: 3 June 2016, last major update June 2016

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: WHO classification of cervical tumors

Table of Contents
Definition / General
Definition / General
Epithelial tumors
  • Squamous cell tumors and precursors
    • Squamous intraepithelial lesions
      • Low-grade squamous intraepithelial lesion
      • High-grade squamous intraepithelial lesion
    • Squamous cell carcinoma, NOS
      • Keratinizing
      • Non-keratinizing
      • Papillary
      • Basaloid
      • Warty
      • Verrucous
      • Squamotransitional
      • Lymphoepithelioma-like
    • Benign squamous cell lesions
      • Squamous metaplasia
      • Condyloma acuminatum
      • Squamous papilloma
      • Transitional metaplasia
  • Glandular tumors and precursors
    • Adenocarcinoma in situ
    • Adenocarcinoma
      • Endocervical adenocarcinoma, usual type
      • Mucinous adenocarcinoma, NOS
        • Gastric type
        • Intestinal type
        • Signet-ring cell type
        • Villoglandular carcinoma
        • Endometrioid adenocarcinoma
        • Clear cell adenocarcinoma
        • Serous adenocarcinoma
        • Mesonephric carcinoma
        • Adenocarcinoma admixed with neuroendocrine carcinoma
  • Benign glandular tumors and tumor-like lesions
    • Endocervical polyp
    • Mullerian papilloma
    • Nabothian cyst
    • Tunnel clusters
    • Microglandular hyperplasia
    • Lobular endocervical glandular hyperplasia
    • Diffuse laminar endocervical hyperplasia
    • Diffuse laminar endocervical hyperplasia
    • Mesonephric remnants and hyperplasia
    • Arias Stella reaction
    • Endocervicosis
    • Endometriosis
    • Tuboendometriod metaplasia
    • Ectopic prostate tissue
  • Other epithelial tumors
    • Adenosquamous carcinoma
    • Glassy cell carcinoma
    • Adenoid cystic carcinoma
    • Adenoid basal carcinoma
    • Neuroendocrine tumors
      • Low-grade neuroendocrine tumor
        • Carcinoid tumor
        • Atypical carcinoid tumor
      • High-grade neuroendocrine tumor
        • Small cell neuroendocrine carcinoma
        • Large cell neuroendocrine carcinoma
    • Undifferentiated carcinoma

Mesenchymal tumors and tumor-like conditions
  • Benign
    • Leiomyoma
    • Rhabdomyoma
    • Others
  • Malignant
    • Leiomyosarcoma
    • Rhabdomyosarcoma
    • Alveolar soft-part sarcoma
    • Angiosarcoma
    • Malignant peripheral nerve sheath tumor
    • Other sarcomas
      • Liposarcoma
      • Undifferentiated endocervical sarcoma
      • Ewing sarcoma
  • Tumor-like lesions
    • Postoperative spindle cell nodule
    • Lymphoma-like lesion

Mixed epithelial and mesenchymal tumors
  • Carcinosarcoma (malignant mullerian mixed tumor)
  • Adenosarcoma
  • Adenomyoma

Melanocytic tumors
  • Malignant melanoma
  • Blue nevus

Germ cell tumors
  • Yolk sac tumor

Lymphoid and myeloid tumors
  • Lymphomas
  • Myeloid neoplasms

Secondary tumors