Table of Contents
Definition / general | Case reports | Microscopic (histologic) description | Microscopic (histologic) imagesCite this page: Adenosarcoma with sarcomatous overgrowth. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cervixadenosarcomasarcomatous.html. Accessed December 6th, 2019.
Definition / general
- Aggressive variant (Am J Surg Pathol 1989;13:28)
- Seen in approximately 10% of cases
- Stromal overgrowth is defined as pure sarcoma representing ≥ 25% of the tumor
- The sarcoma can be homologous or heterologous, and frequently displays high grade cytologic features
Case reports
- 37 year old woman with clinical endocervical polyp (Int J Gynecol Cancer 2004;14:1024)
Microscopic (histologic) description
- Pure sarcoma (not associated with glands) representing 25% of the tumor volume or more
- Stromal overgrowth typically has a high grade cytomorphology
- However, low grade morphology has also been documented (Int J Gynecol Pathol 2014;33:573)
- Rhabdomyosarcomatous differentiation can be observed
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