Adenosarcoma with sarcomatous overgrowth

Cervix
Sarcoma / lymphoma / other
Adenosarcoma with sarcomatous overgrowth

Author: Carlos Parra-Herran, M.D. (see Authors page)

Revised: 2 May 2017, last major update April 2017

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PubMed Search: Adenosarcoma with sarcomatous overgrowth

Related topics: Adenosarcoma

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Table of Contents

Definition / general | Case reports | Microscopic (histologic) description | Microscopic (histologic) images

Cite this page: Adenosarcoma with sarcomatous overgrowth. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cervixadenosarcomasarcomatous.html. Accessed December 6th, 2019.

Definition / general

Aggressive variant (Am J Surg Pathol 1989;13:28)
Seen in approximately 10% of cases
Stromal overgrowth is defined as pure sarcoma representing ≥ 25% of the tumor
The sarcoma can be homologous or heterologous, and frequently displays high grade cytologic features

Case reports

37 year old woman with clinical endocervical polyp (Int J Gynecol Cancer 2004;14:1024)

Microscopic (histologic) description

Pure sarcoma (not associated with glands) representing 25% of the tumor volume or more
Stromal overgrowth typically has a high grade cytomorphology
However, low grade morphology has also been documented (Int J Gynecol Pathol 2014;33:573)
Rhabdomyosarcomatous differentiation can be observed

Microscopic (histologic) images

Images hosted on Pathout server:

Contributed by Carlos Parra-Herran, M.D.