Cervix
Sarcoma / lymphoma / other
Adenosarcoma with sarcomatous overgrowth

Author: Carlos Parra-Herran, M.D. (see Authors page)

Revised: 2 May 2017, last major update April 2017

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PubMed Search: Adenosarcoma with sarcomatous overgrowth

Related topics: Adenosarcoma
Cite this page: Adenosarcoma with sarcomatous overgrowth. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cervixadenosarcomasarcomatous.html. Accessed June 27th, 2017.
Definition / general
  • Aggressive variant (Am J Surg Pathol 1989;13:28)
  • Seen in approximately 10% of cases
  • Stromal overgrowth is defined as pure sarcoma representing ≥ 25% of the tumor
  • The sarcoma can be homologous or heterologous, and frequently displays high grade cytologic features
Case reports
Microscopic (histologic) description
  • Pure sarcoma (not associated with glands) representing 25% of the tumor volume or more
  • Stromal overgrowth typically has a high grade cytomorphology
  • However, low grade morphology has also been documented (Int J Gynecol Pathol 2014;33:573)
  • Rhabdomyosarcomatous differentiation can be observed
Microscopic (histologic) images

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Contributed by Carlos Parra-Herran, M.D.