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Cervix-Cytology

Carcinoma

Adenoid cystic carcinoma

Reviewer: Marilin Rosa, M.D., University of Florida (see Reviewerspage)
Revised: 7 June 2011, last major update June 2011
Copyright: (c) 2006-2011, PathologyOutlines.com, Inc.

Definition
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● Rare and aggressive
● < 1% of cervical adenocarcinomas (Gynecol Oncol 2005;99:477)

Epidemiology
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● Most common in postmenopausal women

Cytology description
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● Small epithelial cells with hyperchromatic nuclei and coarse chromatin surrounding hyaline globular material (Acta Cytol 2010;54:1039)
● H&E shows cribriform pattern (Acta Cytol 1996;40:1304)

Cytology images
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Salivary gland tumor

Positive stains
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● Keratin, type IV collagen, laminin (extracellular basement membrane), HHF45, focal CEA and EMA

Negative stains
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● Usually S100 and actin

End of Cervix-cytology > Carcinoma > Adenoid cystic carcinoma

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