Cervix - Cytology
Carcinoma
Adenoid cystic carcinoma

Author: Ashwyna Sunassee, M.D. (see Authors page)
Editor:Ryan Askeland, M.D.

Revised: 24 April 2017, last major update December 2014

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed Search: Adenoid cystic carcinoma [title] cervix
Cite this page: Adenoid cystic carcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cervixcytologyadenoidcystic.html. Accessed April 27th, 2017.
Definition / General
Epidemiology
Pathophysiology
Clinical Features
  • Postmenopausal bleeding is most common presentation
Radiology Description
  • MRI: T1 weighted images exhibit homogenous low signal intensity T2 weighted images shows high signal intensity with a lobulated contour and multiple septum-like internal architectures, probably representing intergladular fibrous stroma (Eur Radiol 2005;15:975)
Prognostic Factors
  • Poor prognosis due to widespread lymph node and vascular metastases
  • Most common site of metastasis is lung
Treatment
  • Combination of radical pelvic surgery, radiotherapy and chemotherapy
  • Stage I patients: local therapy is adequate
Gross Description
  • Grayish white growth on cervix
Micro Images

Images hosted on other servers:

Cribriform growth

Cytology Description
Positive Stains
Negative Stains
Differential Diagnosis
  • Adenoid basal carcinoma: no intraluminal hyaline, smaller and less pleomorphic nuclei, less aggressive, negative for laminin and type IV collagen