Adenoid cystic carcinoma
Reviewer: Marilin Rosa, M.D., University of Florida (see Reviewerspage)
Revised: 7 June 2011, last major update June 2011
Copyright: (c) 2006-2011, PathologyOutlines.com, Inc.
● Rare and aggressive
● < 1% of cervical adenocarcinomas (Gynecol Oncol 2005;99:477)
● Most common in postmenopausal women
● Small epithelial cells with hyperchromatic nuclei and coarse chromatin surrounding hyaline globular material (Acta Cytol 2010;54:1039)
● H&E shows cribriform pattern (Acta Cytol 1996;40:1304)
Salivary gland tumor
● Keratin, type IV collagen, laminin (extracellular basement membrane), HHF45, focal CEA and EMA
● Usually S100 and actin
End of Cervix-cytology > Carcinoma > Adenoid cystic carcinoma
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