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Benign / non-neoplastic lesions


Reviewer: Farnaz Hasteh, M.D., UCSD Medical Center (see Reviewers page)
Revised: 2 November 2010, last major update October 2010
Copyright: (c) 2006-2010, PathologyOutlines.com, Inc.


● Well circumscribed tumor composed of uterine smooth muscle and endometrial or endocervical type glands, usually without atypia


● May have glands of endocervical type (Mod Pathol 1996;9:220) or endometrial type

Case reports

● With endometrial type glands and bizarre nuclei resembling leiomyosarcoma on smear (Diagn Cytopathol 2005;32:288)

Cytology description

● Clusters or individual endocervical or endometrial type cells and smooth muscle cells, with delicate wispy cytoplasm, oval nuclei with nucleoli
● Smooth muscle cells may have large and bizarre nuclei, but no mitotic figures, no necrosis

Differential diagnosis

Atypical polypoid adenomyoma: tightly backed clusters of glandular cells and loose aggregates of bland smooth muscle cells in premenopausal patients (Diagn Cytopathol 2000;22:176)

End of Cervix-cytology > Benign / non-neoplastic lesions > Adenomyoma

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