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Cervix-Cytology
Normal cells /
non-neoplastic findings
Air drying
artifact
Reviewer: Varsha Manucha, M.D. (see Reviewers page)
Revised: 2 October 2010, last major update August 2010
Copyright: (c) 2006-2010, PathologyOutlines.com, Inc.
Definition / general
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● Artifact due to delay in immersion in alcohol fixative (Hong Kong Society of Cytology, Section 2.4.3)
● More
common on conventional than liquid based smears
● Specimen is unsatisfactory if more than 75% of cells show air drying; if less
extensive, may be mentioned as a quality indicator
● May cause discrepant diagnosis of LSIL or underdiagnosis for HSIL smears
(Cancer 2002;96:218, Indian J Cancer 2004;41:104)
● Associated with ASCUS in perimenopausal women
(Cancer 2001;93:100)
Cytology description
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● Cells are degenerated, eosinophilic, enlarged and lightly stained
● Nuclei are pale, flattened and lack chromatin detail
Cytology images
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Sheets of parabasal cells with slight air drying
Sheets of parabasal cells with slight air drying
ASC-US
HSIL
End of
Cervix-cytology > Normal cells / non-neoplastic findings > Air drying
artifact
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