Home   Chapter Home   Jobs   Conferences   Fellowships   Books



Atypia / premalignant / preinvasive lesions

Atypical repair

Reviewer: Marilin Rosa, M.D., University of Florida (see Reviewers page)
Revised: 8 June 2011, last major update June 2011
Copyright: (c) 2002-2011, PathologyOutlines.com, Inc.


● Part of ASC-US category in Bethesda 2001
● 5% incidence of SIL in one study (Diagn Cytopathol 2005;33:214)


● Few cohesive tissue fragments, uniform nuclei, chromatin with increased chromatin granules, hyperchromasia, prominent nucleoli, scarce mitotic activity
Liquid based cytology: scattered atypical squamous cells with prominent nucleoli and other evidence of reparative change; also more obvious nuclear pleomorphism, anisonucleosis, nuclear outline irregularities, coarsening of chromatin and focal loss of nuclear polarity (Cancer 2003;99:141)

Differential Diagnosis

● Poorly differentiated squamous cell carcinoma or adenocarcinoma

End of Cervix-cytology > Atypia / premalignant / preinvasive lesions > Atypical repair

This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at [email protected] with any questions (click here for other contact information).