Cervix Cytology - Atypical reserve cell hyperplasia

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Cervix-Cytology

Atypia / premalignant / preinvasive lesions

Atypical reserve cell hyperplasia

Reviewer: Marilin Rosa, M.D., University of Florida (see Reviewers page)
Revised: 8 June 2011, last major update June 2011
Copyright: (c) 2002-2011, PathologyOutlines.com, Inc.

Cytology description
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● No cytoplasm seen (Mod Pathol 1995;8:786, Acta Cytol 1978;22:305), because cells are easily damaged in smear process
● Cells in pairs, clusters or rows, with nuclear molding often present
● Isolated naked nuclei are prominent
● May be considered a variant of SIL (Tavassoli: Tumours of the Breast and Female Genital Organs, WHO, 3rd Ed, Vol 4)

Positive stains
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● Ki-67/MIB1

Differential Diagnosis
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● Artifact
● Degenerated cells
● Adenocarcinoma

End of Cervix-cytology > Atypia / premalignant/ preinvasive lesions > Atypical reserve cell hyperplasia

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