Cervix Cytology - Blue blobs

Home Chapter Home Jobs Conferences Fellowships Books

Cervix-Cytology

Normal cells / non-neoplastic findings

Blue blobs

Reviewer: Varsha Manucha, M.D. (see Reviewers page)
Revised: 28 September 2010, last major update August 2010
Copyright: (c) 2006-2010, PathologyOutlines.com, Inc.

Definition
=========================================================================

● Represent condensed mucus, degenerated bare nuclei or precipitating hematoxylin
● In post-menopausal women, represent parabasal/intermediate squamous cells with various degrees of degeneration (Acta Cytol 2000;44:547)
● May have "string of pearls” appearance on ThinPrep in postmenopausal atrophy (Diagn Cytopathol 2009;38:233)

Cytology description
=========================================================================

● Dark blue, rounded, amorphous masses

Cytology images
=========================================================================

Liquid based cytology with amorphous basophilic material

Positive stains
=========================================================================

● Periodic acid-Schiff and methyl green pyronin, cytokeratin, epithelial membrane antigen and carcinoembryonic antigen (Acta Cytol 2000;44:547)

Negative stains
=========================================================================

● Mucicarmine and calcium, vimentin and muscle specific actin (Acta Cytol 2000;44:547)

Electron microscopy descriptions
=========================================================================

● Cellular skeletons with residual tonofilaments enmeshed within a loose cytoskeleton matrix and nuclei with variable degrees of degeneration (Acta Cytol 2000;44:547)

End of Cervix-cytology > Normal cells / non-neoplastic findings > Blue blobs

This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).