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Normal cells /
Reviewer: Varsha Manucha, M.D. (see Reviewers page)
Revised: 28 September 2010, last major update August 2010
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● Represent condensed mucus, degenerated bare nuclei or precipitating hematoxylin
● In post-menopausal women, represent parabasal/intermediate squamous cells with various degrees of degeneration (Acta Cytol 2000;44:547)
● May have "string of pearls” appearance on ThinPrep in postmenopausal atrophy (Diagn Cytopathol 2009;38:233)
● Dark blue, rounded, amorphous masses
Liquid based cytology with amorphous basophilic material
● Periodic acid-Schiff and methyl green pyronin, cytokeratin, epithelial membrane antigen
and carcinoembryonic antigen (Acta Cytol 2000;44:547)
● Mucicarmine and calcium, vimentin and muscle specific actin
(Acta Cytol 2000;44:547)
Electron microscopy descriptions
● Cellular skeletons with residual tonofilaments enmeshed within a loose cytoskeleton matrix
and nuclei with variable degrees of degeneration (Acta Cytol 2000;44:547)
Cervix-cytology > Normal cells / non-neoplastic findings > Blue blobs
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