Cervix - Cytology
Cytopathology Competency / Milestone Assessment - The Pap Test
4. Effects of Therapeutic Agents



Topic Completed: 1 January 2014

Revised: 3 January 2019, last major update January 2014

Copyright: (c) 2014-2017, PathologyOutlines.com, Inc.

PubMed search: Cytopathology Therapeutic Agents [title] effects


Zubair W. Baloch, M.D., Ph.D.
Ricardo R. Lastra, M.D.
Page views in 2018: 260
Page views in 2019 to date: 152
Cite this page: Lastra R., Baloch Z. Cytology - Effects of Therapeutic Agents. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cervixcytologycompeffects.html. Accessed September 23rd, 2019.
Medical knowledge
  1. Recognize the morphology associated to the presence of intrauterine devices (IUDs)
  2. Recognize the morphology of acute and chronic radiation change
  3. Recognize the morphology of acute and chronic radiation change
  4. Recognize the changes seen in exogenous estrogen or progesterone administration
Practice based learning and systems based practice
  1. Understand how to differentiate postradiation and chemotherapy changes from recurrent / residual carcinoma
  2. Understand how to differentiate atypical cells associated to IUDs from neoplastic disease
    • Hypervacuolated endocervical cells
    • Hypervacuolated metaplastic cells
    • Endometrial cells
  3. Understand the utility of topical estrogen therapy in evaluation of atrophic pattern Pap smears
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