Normal cells / nonneoplastic findings

Topic Completed: 1 August 2010

Minor changes: 5 March 2020

Copyright: 2010-2020, PathologyOutlines.com, Inc.

PubMed search: Cornflake

Xinmin Zhang, M.D.
Page views in 2019: 961
Page views in 2020 to date: 454
Cite this page: Zhang X. Cornflakes. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cervixcytologycornflakes.html. Accessed May 29th, 2020.
Definition / general
  • Distinctive appearance is due to evaporation of xylene before cover slipping with deposition of air on superficial squamous cells
  • More common on conventional than liquid based preparations
  • It can be reversed by returning the slides through xylene and alcohol to water then restaining and recoverslipping
  • Also called "brown artifact," cornflaking
Cytology images

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Contributed by Dr. Yao-Wen Liu, Kuo General Hospital, Taiwan

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