Cervix - Cytology
Normal cells / nonneoplastic findings

Author: Xinmin Zhang, M.D. (see Authors page)

Revised: 27 April 2017, last major update August 2010

Copyright: (c) 2006-2017, PathologyOutlines.com, Inc.

PubMed search: degeneration cervix cytology

Cite this page: Degeneration. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cervixcytologydegeneration.html. Accessed September 25th, 2018.
Definition / general
  • Degenerative type changes due to delay in transfer of cells to the slide (air drying artifact), inflammation or atrophy
  • More common on conventional than liquid based preparations
  • Occasionally called retroplastic change
Cytology description
  • Cytoplasm is lost and moth eaten with vacuolization
  • Chromatin is clumped, hazy, smudged or indistinct
  • Chromatin rim has variable thickness and irregular contours but no sharp angles of malignancy
Cytology images

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Degenerated cells