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Normal cells / non-neoplastic findings

Endocervical cells

Reviewer: Xinmin Zhang, M.D., Temple University (see Reviewers page)
Revised: 14 June 2011, last major update August 2010
Copyright: (c) 2006-2010, PathologyOutlines.com, Inc.

Definition / General

● Most effective device for collection appears to be cytobrush and extended tip spatula (Cochrane Database Syst Rev 2000;CD001036)
● Presence of endocervical cells indicates that the upper limit of transformation zone was included, so collection is adequate

Cytology description

● Usually columnar cells (2 mm) with vacuolated or granular cytoplasm, prominent cell borders, basal nuclei with fine granular chromatin and occasional nucleoli
● Often identified in strips or sheets with mucin production that may results in cup-shaped nuclei
● Honeycomb appearance en face
● Ciliated if tubal metaplasia

Cytology images


Various images     Secretory cells     Ciliated cells


Large clusters of cells

En face

Tubal metaplasia



Liquid based cytology


Various images          En face                    Tubal metaplasia

End of Cervix-cytology > Normal cells / non-neoplastic findings > Endocervical cells

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