Cervix - Cytology
Normal cells / nonneoplastic findings
Endometrial cells



Topic Completed: 1 August 2010

Revised: 2 October 2019

Copyright: (c) 2006-2017, PathologyOutlines.com, Inc.

PubMed search: cervix endometrial cells [title]


Xinmin Zhang, M.D.
Page views in 2019: 1,746
Page views in 2020 to date: 138
Cite this page: Zhang X. Endometrial cells. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cervixcytologyendometrialcells.html. Accessed January 27th, 2020.
Definition / general
  • Spontaneously exfoliated endometrial cells are often seen during the first 12 days of the menstrual cycle
  • May also be due to hormone replacement therapy (Obstet Gynecol 2002;100:445) or tamoxifen
  • Endocervical sampling devices may inadvertently sample the lower uterine segment or endometrium
Clinical features
Cytology description
  • Exfoliated endometrial cells often present as small cells arranged in balls with scant cytoplasm, dark nuclei and nuclear molding and fragmentation
  • Abraded endometrial cells may present as large and small tissue fragments with glands and stromal cells
  • Resemble histiocytes
  • Easier to identify if in clusters
Cytology images

Images hosted on PathOut server:

Thin Prep of normal endometrial
group - postmenstrual cycle,
contributed by Dr. Carmen Luz, Spain



Images hosted on other servers:
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IUD related changes

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endometrial cells (40x)

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