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Cervix-Cytology
Normal cells / non-neoplastic findings
Histiocytes
Reviewer: Marilin Rosa, M.D., University of Florida (see Reviewers
page)
Revised: 6 October 2010, last major update August 2010
Copyright: (c) 2006-2010, PathologyOutlines.com, Inc.
Definition / General
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● Nonspecific finding; clinical history is more predictive of endometrial pathology than presence of histiocytes
(Acta Cytol 2003;47:135,
Acta Cytol 2003;47:762)
Cytology description
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● Larger than neutrophils, vacuolated or frothy cytoplasm (scant to moderate), round to reniform (bean shaped) nuclei that is central or eccentric, chromatin fine to coarse but uniformly distributed, nucleoli variable
● Epithelioid histiocytes: usually in aggregates
● Multinucleated histiocytes: randomly arranged nuclei with granular chromatin
Cytology images
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Various images
Histiocytes
Multinucleated histiocytes
End of
Cervix-cytology > Normal cells / non-neoplastic findings > Histiocytes
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