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Normal cells / non-neoplastic findings


Reviewer: Marilin Rosa, M.D., University of Florida (see Reviewers page)
Revised: 6 October 2010, last major update August 2010
Copyright: (c) 2006-2010, PathologyOutlines.com, Inc.

Definition / General

● Nonspecific finding; clinical history is more predictive of endometrial pathology than presence of histiocytes (Acta Cytol 2003;47:135, Acta Cytol 2003;47:762)

Cytology description

● Larger than neutrophils, vacuolated or frothy cytoplasm (scant to moderate), round to reniform (bean shaped) nuclei that is central or eccentric, chromatin fine to coarse but uniformly distributed, nucleoli variable
Epithelioid histiocytes: usually in aggregates
Multinucleated histiocytes: randomly arranged nuclei with granular chromatin

Cytology images


Various images




Multinucleated histiocytes

End of Cervix-cytology > Normal cells / non-neoplastic findings > Histiocytes

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