Benign cells / nonneoplastic lesions
Intermediate squamous cells

Topic Completed: 1 June 2011

Minor changes: 26 March 2020

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PubMed search: Intermediate squamous cells [title]

Marilin Rosa, M.D.
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Cite this page: Rosa M. Intermediate squamous cells. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cervixcytologyintermediatesquamous.html. Accessed June 1st, 2020.
Definition / general
  • Predominate in luteal phase
  • Presence of nuclear grooves is not associated with inflammation; in smears with neoplastic changes, is associated with HSIL (Acta Cytol 2003;47:421)
Cytology description
  • Cytoplasm is polygonal, transparent, basophilic, flat / thin
  • Nucleus is about the size of a red blood cell, is vesicular, round / oval; nuclear texture and size is reference for dysplasia
  • May see cytolysis / dirty background, Doderlein bacilli
Cytology images

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Intermediate scamous cells

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Normal ectocervix

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