Home   Chapter Home   Jobs   Conferences    Fellowships    Books



Advertisement

Cervix-Cytology

Benign / non-neoplastic lesions

Lobular endocervical glandular hyperplasia of cervix, NOS


Reviewer: Farnaz Hasteh, M.D., UCSD Medical Center (see Reviewers page)
Revised: 20 September 2012, last major update December 2010
Copyright: (c) 2006-2012, PathologyOutlines.com, Inc.

Definition
========================================================================

● Pseudoneoplastic glandular lesion of cervix
● Not neoplastic (Am J Surg Pathol 1999;23:886)

Clinical features
========================================================================

● May be associated with endocervical adenocarcinoma (Mod Pathol 2005;18:1199)

Cytology description
========================================================================

● Hyperplastic glandular lesions with lobular arrangements, but no desmoplastic stroma
● Hyperplastic lesions are composed of high columnar mucinous cells with no atypia and no/rare mitotic figures
● Benign looking glandular cells have intracytoplasmic golden-yellow mucin (Diagn Cytopathol 2002;27:80)
● Intranuclear cytoplasmic inclusions usually are present

Cytology images
========================================================================


Microscopic images

Benign glandular cells with golden-yellow mucin (figures c and d)

Differential diagnosis
========================================================================

● Minimal deviation adenocarcinoma: may also have golden yellow mucin, but has focally malignant cytologic features, three dimensional cell clustering, prominent nucleoli, no intracellular cytoplasmic inclusions (Pathol Int 2005;55:412, Diagn Cytopathol 2008;36:535)

End of Cervix-cytology > Benign / non-neoplastic lesions > Lobular endocervical glandular hyperplasia of cervix, NOS


This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).