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Cervix-Cytology

Carcinoma

Lymphoepithelioma-like carcinoma


Reviewer: Marilin Rosa, M.D., University of Florida (see Reviewers page)
Revised: 9 June 2011, last major update June 2011
Copyright: (c) 2002-2011, PathologyOutlines.com, Inc.

Definition
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● Tumor similar to lymphoepithelial carcinoma of nasopharynx and morphologically characterized by large tumor cells with prominent nucleoli usually growing in syncytial sheets and associated with an intense inflammatory infltrate, mainly consisting of lymphocytes (Arch Gynecol Obstet 2009;280:725)

Prognostic factors
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● Better outcome than other cervical neoplasms

Cytology
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● Uniform large tumor cells, indistinct cell borders, finely granular cytoplasm, round/oval nuclei and prominent nucleoli, marginated chromatin
● No koilocytes, no gland formation, no keratinization (Acta Cytol 1999;43:285)

Differential Diagnosis
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● Poorly differentiated squamous cell carcinoma
● Lymphoproliferative disorders of the cervix

End of Cervix-cytology > Carcinoma > Lymphoepithelioma-like carcinoma


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