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Cervix-cytology

Sarcoma / lymphoma / other

Lymphoma

Reviewer: Nat Pernick, M.D., PathologyOutlines.com, Inc. (see Reviewers page)
Revised: 26 June 2011, last major update June 2011
Copyright: (c) 2006-2011, PathologyOutlines.com, Inc.

General
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● Usually presents with abnormal uterine or vaginal bleeding
● Cervical smear may be first indication of tumor, but smear is often negative or reported as SIL
● Usually diffuse large B cell or follicular subtypes (Mod Pathol 2000;13:19)

Case reports
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● 42 year old woman with Burkitt’s lymphoma with HSIL (Pathol Res Pract 2005;201:521)
● Two patients with diffuse large B cell lymphoma and follicular lymphoma at biopsy but HSIL by pap smear (Gynecol Oncol 2005;98:484)
● Three patients with atypical lymphoid cells at pap smear (Am J Hematol 2003;73:176)
● Detection of HTLV-1 (in adult T cell leukemia / lymphoma) by PCR on cytologic smears (Methods Mol Biol 2005;304:183)

Cytology description
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● Round, loosely arranged neoplastic cells with scanty cytoplasm (Cytopathology 1996;7:204)

Cytology images
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Various images


Large cell lymphoma


Liquid based cytology

Differential diagnosis
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● Chronic cervicitis: ThinPrep specimens may show clumps of lymphocytes (Cytopathology 2002;13:364)

End of Cervix-cytology > Sarcoma / lymphoma / other > Lymphoma

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