Benign cells / nonneoplastic lesions
Maturation index

Topic Completed: 1 June 2011

Minor changes: 10 March 2020

Copyright: 2011-2020, PathologyOutlines.com, Inc.

PubMed search: Maturation index [title]

Nat Pernick, M.D.
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Table of Contents
Definition / general
Cite this page: Pernick N. Maturation index. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cervixcytologymaturationindex.html. Accessed June 1st, 2020.
Definition / general
  • Defined as ratio of parabasal to intermediate to superficial cells of vaginal epithelium (sampled at middle third of lateral vaginal wall)
  • Sample often obtained simultaneous with Pap smear
  • For detecting hormonal effects in menopausal and postmenopausal women
  • Increased maturation in vaginal epithelium may be due to estrogenic effect of tamoxifen (Clin Exp Obstet Gynecol 1998;25:121)
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