Home   Chapter Home   Jobs   Conferences   Fellowships   Books

Advertisement

Cervix-cytology

Sarcoma / lymphoma / other

Melanoma

Reviewer: Nat Pernick, M.D., PathologyOutlines.com, Inc. (see Reviewers page)
Revised: 27 June 2011, last major update June 2011
Copyright: (c) 2006-2011, PathologyOutlines.com, Inc.

General
=========================================================================

● Rare tumor; usually post-menopausal women (Cytojournal 2010 Dec 31;7:25)

Case reports
=========================================================================

● Amelanotic metastatic tumor presenting as cervical polyp (Acta Cytol 1985;29:612)

Cytology description
=========================================================================

● Tumor cells with occasional cytoplasmic brown pigment, often bizarre shape; hyperchromatic and irregular nuclei, prominent nucleoli
● Also necrosis, occasional mitotic figures

Cytology images
=========================================================================

   
Primary tumor: Pap staining


Primary tumor: liquid based cytology

   
Metastatic tumors


Vaginal tumor

Positive stains
=========================================================================

● S100, HMB45, vimentin, Ki-67 (high percentage)

Negative stains
=========================================================================

● Keratin, CD45, ER, PR

Additional references
=========================================================================

● Cytopathology 2003;14:153, Diagn Cytopathol 2001;25:108, Acta Cytol 1994;38:65

End of Cervix-cytology > Sarcoma / lymphoma / other > Melanoma

This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).