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Cervix-cytology

Sarcoma / lymphoma / other

Melanoma


Reviewer: Nat Pernick, M.D., PathologyOutlines.com, Inc. (see Reviewers page)
Revised: 27 June 2011, last major update June 2011
Copyright: (c) 2006-2011, PathologyOutlines.com, Inc.

General
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● Rare tumor; usually post-menopausal women (Cytojournal 2010 Dec 31;7:25)

Case reports
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● Amelanotic metastatic tumor presenting as cervical polyp (Acta Cytol 1985;29:612)

Cytology description
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● Tumor cells with occasional cytoplasmic brown pigment, often bizarre shape; hyperchromatic and irregular nuclei, prominent nucleoli
● Also necrosis, occasional mitotic figures

Cytology images
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Primary tumor: Pap staining


Primary tumor: liquid based cytology

   
Metastatic tumors


Vaginal tumor

Positive stains
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● S100, HMB45, vimentin, Ki-67 (high percentage)

Negative stains
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● Keratin, CD45, ER, PR

Additional references
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Cytopathology 2003;14:153, Diagn Cytopathol 2001;25:108, Acta Cytol 1994;38:65

End of Cervix-cytology > Sarcoma / lymphoma / other > Melanoma


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