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Metastases to cervix

Reviewer: Marilin Rosa, M.D., University of Florida (see Reviewers page)
Revised: 9 June 2011, last major update June 2011
Copyright: (c) 2002-2011, PathologyOutlines.com, Inc.


● Yield for positive Pap smear diagnoses in extrauterine malignancies is best in patients with an established diagnosis (Acta Cytol 1999;43:806)

Case reports

● 17 year old with colon cancer metastatic to cervix presenting with abnormal pap smear (J Reprod Med 2005;50:793)
● 59 year old with recurrent colon carcinoma invading into uterus and cervix and presenting with HSIL at pap smear (J Low Genit Tract Dis 2005;9:236)
● 61 year old with metastatic salivary duct carcinoma (Diagn Cytopathol 1999;21:271)

Cytology images

Metastatic tumors:

Breast carcinoma

Colon carcinoma

Gastric carcinoma


Ovarian clear cell carcinoma with psammoma body (contributed by Dr. Carmen Luz, Spain)

Small cell carcinoma

Urothelial carcinoma

Positive stains

● Immunohistochemistry panels will vary according to site of origin
● Clinical history important when selecting panels of immunostains

End of Cervix-cytology > Carcinoma > Metastases to cervix

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