Atypic / premalignant / preinvasive lesions
Paget disease

Topic Completed: 1 June 2011

Minor changes: 11 March 2020

Copyright: 2002-2020, PathologyOutlines.com, Inc.

PubMed search: Paget disease cervix

Marilin Rosa, M.D.
Page views in 2019: 334
Page views in 2020 to date: 149
Cite this page: Rosa M. Paget disease. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cervixcytologypagets.html. Accessed June 1st, 2020.
Definition / general
  • Extramammary Paget disease of vulva is rare; ~ 2% of vulvar neoplasms (Diagn Cytopathol 2005;32:353)
  • Infrequently involves cervix and vagina and can be detected on pap smears
Case reports
Cytology description
  • Large cells with high N/C ratio, round nuclei, large nucleoli, clumped chromatin and occasional large cytoplasmic vacuoles
  • Alsp pseudocannibalism, signet ring cells
Positive stains
Back to top