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Cervix-Cytology

Inflammation/parasites

Tuberculosis

Reviewer: Farnaz Hasteh, M.D., UCSD Medical Center (see Reviewers page)
Revised: 11 June 2011, last major update March 2011
Copyright: (c) 2006-2011, PathologyOutlines.com, Inc.

Epidemiology
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● Rare in USA but common in developing countries
● Usually fallopian tube involvement

Cytology description
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● Epithelioid histiocytes and Langhans giant cells (peripheral nuclei); background contains caseous necrosis
● Inflammatory infiltrate

Cytology images
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Epithelioid histiocytes

Langhans giant cell with inflammatory background

Acid-fast bacilli


Auramine-rhodamine (site unspecified)

Positive stains
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● Acid fast stain

Molecular / cytogenetics description
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● PCR is useful for diagnosis

Differential diagnosis
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● Foreign body granuloma due to surgery or radiation
● Other infectious cause (granuloma inguinale, lymphogranuloma venereum)

Additional references
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● Acta Cytol 1989;33:305, J Clin Pathol 1976;29:313

End of Cervix-cytology > Inflammation/parasites > Tuberculosis

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